Detalhe da pesquisa
1.
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Cell
; 173(3): 706-719.e13, 2018 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-29677514
2.
Only solid waste, please!
Mol Cell
; 82(8): 1408-1410, 2022 04 21.
Artigo
Inglês
| MEDLINE | ID: mdl-35452612
3.
Liquid-Liquid Phase Separation in Disease.
Annu Rev Genet
; 53: 171-194, 2019 12 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31430179
4.
Post-translational modifications on RNA-binding proteins: accelerators, brakes, or passengers in neurodegeneration?
Trends Biochem Sci
; 47(1): 6-22, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34366183
5.
Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
EMBO J
; 41(8): e108443, 2022 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35112738
6.
The new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis.
Brain
; 2023 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38079474
7.
The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid-liquid phase separation.
Nucleic Acids Res
; 49(13): 7713-7731, 2021 07 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34233002
8.
Nonclassical nuclear localization signals mediate nuclear import of CIRBP.
Proc Natl Acad Sci U S A
; 117(15): 8503-8514, 2020 04 14.
Artigo
Inglês
| MEDLINE | ID: mdl-32234784
9.
Creating overview and summary figures.
Trends Biochem Sci
; 48(2): 97-99, 2023 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-36669467
10.
Nucleocytoplasmic transport defects in neurodegeneration - Cause or consequence?
Semin Cell Dev Biol
; 99: 151-162, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31152789
11.
The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors.
J Biol Chem
; 296: 100659, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33857479
12.
Friend or foe-Post-translational modifications as regulators of phase separation and RNP granule dynamics.
J Biol Chem
; 294(18): 7137-7150, 2019 05 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30587571
13.
Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons.
J Neurosci
; 38(35): 7683-7700, 2018 08 29.
Artigo
Inglês
| MEDLINE | ID: mdl-30054395
14.
Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
Hum Mol Genet
; 26(4): 790-800, 2017 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28040728
15.
Molecular mechanisms of neurodegeneration.
Semin Cell Dev Biol
; 99: 131-132, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31902626
16.
Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.
Acta Neuropathol
; 133(6): 887-906, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28243725
17.
Altered mRNP granule dynamics in FTLD pathogenesis.
J Neurochem
; 138 Suppl 1: 112-33, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-26938019
18.
Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.
EMBO J
; 31(22): 4258-75, 2012 Nov 14.
Artigo
Inglês
| MEDLINE | ID: mdl-22968170
19.
Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS.
Acta Neuropathol
; 131(4): 587-604, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26895297
20.
Nuclear import factor transportin and arginine methyltransferase 1 modify FUS neurotoxicity in Drosophila.
Neurobiol Dis
; 74: 76-88, 2015 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-25447237